منابع مشابه
Tumor markers: from laboratory to clinical utility.
1 Department of Pharmacology and Pathobiology, Royal Veterinary and Agricultural University, Ridebanevej 9, DK-1870 Frederiksberg C, Copenhagen, Denmark. 2 Department of Chemical Endocrinology, University Medical Centre Nijmegen, P.O. Box 9101 Geert Groteplein 10, NL-6500 HB Nijmegen, The Netherlands. 3 Clinical Research Unit, Department of Obstetrics & Gynaecology, Technical University of Muni...
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Introduction of tumor markers into routine clinical practice has been poorly controlled, with few criteria or guidelines as to how such markers should be used. We propose a Tumor Marker Utility Grading System (TMUGS) to evaluate the clinical utility of tumor markers and to establish an investigational agenda for evaluation of new tumor markers. A Tumor Marker Utility Grading Worksheet has been ...
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Because alcoholism is a multi-factorial psychiatric disorder, with both psychosocial and biochemical/genetic factors leading to its manifestation in any one individual, the presence of biochemical/ genetic factors alone may not lead to the manifestation of the disorder. There are numerous difficulties associated with identification of a trait abnormality in a disorder that requires suitable soc...
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Although a myriad of markers have been proposed for malignancy, only a minority have been adequately validated for routine clinical use. Apart from PSA in prostate cancer, markers are of little value in the detection of early malignancy. Several markers however, are currently used in the post-operative management of patients with diagnosed malignancy. Markers generally recommended for the manag...
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The molecular analysis of biomarkers in oncology is rapidly advancing, but the incorporation of new molecular tests into clinical practice will require a greater understanding of the genetic changes that drive malignancy, the assays used to measure the resulting phenotypes and genotypes, and the regulatory processes that new molecular biomarkers must face to be accepted for clinical use. To add...
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ژورنال
عنوان ژورنال: Jugoslovenska medicinska biohemija
سال: 2006
ISSN: 0354-3447
DOI: 10.2298/jmb0602119i